Altered interaction between enteric glial cells and mast cells in the colon of women with irritable bowel syndrome
نویسندگان
چکیده
منابع مشابه
The Role of Mast Cells in Irritable Bowel Syndrome
Irritable bowel syndrome (IBS) is one of the most common functional gastrointestinal disorders, but its treatment is unsatisfactory as its pathophysiology is multifactorial. The putative factors of IBS pathophysiology are visceral hypersensitivity and intestinal dysmotility, also including psychological factors, dysregulated gut-brain axis, intestinal microbiota alterations, impaired intestinal...
متن کاملActivated mast cells infiltrate in close proximity to enteric nerves in diarrhea-predominant irritable bowel syndrome.
Mast cells (MC) may be one factor influencing the response of visceral afferent nerves to mechanical and chemical stimuli. The aim of this study was to evaluate the degree of infiltration and activity of colonic MC in irritable bowel syndrome (IBS). Biopsy specimens were obtained from the cecum and rectum of 14 diarrhea predominant IBS and 14 normal controls. Electron microscopy was used to det...
متن کاملIrritable bowel syndrome - An inflammatory disease involving mast cells
Irritable bowel syndrome (IBS) is traditionally defined as a functional disorder - that is the presence of symptoms in the absence of demonstrable pathological abnormalities. In recent times, low grade inflammatory infiltrates in both the small and large bowel of some patients with IBS - often rich in mast cells, along with serological markers of low grade inflammation have focussed attention o...
متن کاملAnd Food Allergies System in the Irritable Bowel Syndrome, Enteritis, Histamine, Mast Cells, and the Enteric Nervous Rapid Responses
These include: References http://gut.bmjjournals.com/cgi/content/full/55/4/445#BIBL This article cites 26 articles, 4 of which can be accessed free at: Rapid responses http://gut.bmjjournals.com/cgi/eletter-submit/55/4/445 You can respond to this article at: service Email alerting top right corner of the article Receive free email alerts when new articles cite this article sign up in the box at...
متن کاملInteraction between ingested nutrients and gut endocrine cells in patients with irritable bowel syndrome (Review)
Several endocrine cell abnormalities have been reported in different segments of the gastrointestinal tract of patients with irritable bowel syndrome (IBS). These cells have specialized microvilli that project into the lumen; they function as sensors for the gut contents and respond to luminal stimuli (mostly ingested nutrients) by releasing hormones into the lamina propria, where they exert th...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Neurogastroenterology & Motility
سال: 2021
ISSN: 1350-1925,1365-2982
DOI: 10.1111/nmo.14130